Sequence analysis A cautionary note on using binary calls for analysis of DNA methylation

A cautionary note on using binary calls for analysis of DNA methylation Agnieszka Prochenka*, Piotr Pokarowski, Piotr Gasperowicz, Joanna Kosińska, Piotr Stawiński, Renata Zbieć-Piekarska, Magdalena Spólnicka, Wojciech Branicki and Rafał Płoski* Institute of Computer Science, Polish Academy of Sciences, Jana Kazimierza 5, Warsaw, Poland, Department of Medical Genetics, Medical University of Warsaw, Pawińskiego 3c, Warsaw, Poland, Faculty of Mathematics, Informatics and Mechanics, University of Warsaw, Banacha 2, Warsaw, Poland, Department of Immunology, Center for Biostructure Research, Medical University of Warsaw, Banacha 2, Warsaw, Poland, Central Forensic Laboratory of the Police, Aleje Ujazdowskie 7, Warsaw, Poland and Institute of Forensic Research, Westerplatte 9, Krakow, Poland